The Washington Manual of Medical Therapeutics is a good handbook reference for the internal medicine rotation. It's descriptions of diseases can be succinct, but the book covers other aspects such as imaging and treatment well. The main drawback to the book is its size. The spiral bound can add a couple of pounds of weight to a white coat; a paper bound copy seems to be more compact. Overall, The Washington Manual is a good reference to have when free time is available during the day.