
Aortic Stenosis with post obstructive dilation and coarction.
| Subjective |
| 34 year old white male presents with dry patches on his scalp, back of his elbows, and the front of his knees. They have been present for several months. No itching. |
| Objective |
| Vital signs stable. Skin - dry, scaling plaques, well-circumscribed, silver present on scalp, extensor surfaces of elbow and knee |
| Assessment and Plan |
| A- Psoriasis P- topical corticosteroids, other options include ultraviolet light (sunlight), lubricants, and keratolytics |
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| Subjective |
| 75 year old male presents with ulcers in his mouth. Started five months ago. Ulcers have progressed to around his mouth and on his forearms. |
| Objective |
| Vitals signs stable. Oral- multiple bullae in mucosa Skin - multiple bullae Labs - biopsy shows antibody pattern in fish-net immunofluorescence pattern |
| Assessment and Plan |
| A- Pemphigus P- corticosteroids |
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| Subjective |
| 45 year old female presents with painful, red nodules on her shins. Started 1 month ago. Patient was recently diagnosed with ulcerative colitis. |
| Objective |
| Vital signs stable Extremities - pretibial, tender, erythematous nodules |
| Assessment and Plan |
| DDX - sarcoidosis, coccidiomycosis, ulcerative colitis, streptococcal infection, idiopathic A - erythema nodosum due to ulcerative colitis P - treat ulcerative colitis |
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| Subjective |
| 25 year old patient notes a growth on her forehead which is the color of her skin. It started about 2 months ago and has stopped growing. |
| Objective |
| Vital signs stable. Skin - flesh colored lesion on forehead with central crater, crater contains keratinous material |
| Assessment and Plan |
| A - Keratocanthoma P - Lesion will likely resolve in a few months, observation for few months, biopsy if needed. |
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Substance | Intoxication | Withdrawal |
Alcohol | - (1+) Slurred speech - Incoordination - Unsteady gait - Nystagmus - Impairment in attention or memory - Stupor or coma (t) folate 1mg , thiamine 100mg | - (2+) Autonomic hyperactivity - Increased hand tremor - Insomnia - Nausea or vomiting - Transient visual, tactile, or auditory hallucinations - Psychomotor agitation - Anxiety - Grand mal seizures (t) Benzodiazepines - oxazepam, IV; Dilantin; Haldol |
Cocaine / Amphetamine | - (2+) Tachycardia or bradycardia - Pupillary dilation - Elevated or lowered blood pressure - Perspiration or chills - Nausea or vomiting - Evidence of weight loss - Psychomotor agitation or retardation - Muscular weakness, respiratory depression, chest pain, or cardiac arrhythmias - Confusion, seizures, dyskinesias, dystonias, or coma (t) self-limited, anti-psychotics | - (2+) Dysmorphic mood - Fatigue - Vivid, unpleasant dreams - Insomnia or hypersomnia - Increased appetite - Psychomotor retardation or agitation (t) self-limited, observation |
Opiates - morphine - codeine - meperidine - hydromorphone | - papillary constriction (dilation) - (1+) drowsiness or coma - slurred speech - impairment in attention or memory - euphoria > dysphoria - psychomotor agitation or retardation - impaired judgement (t) Methadone 5-20 mg> 60-100 mg | - (3+) dysphoric mood - nausea or vomiting - muscle aches - lacrimation or rhinorrhea - papillary dilation, piloerection, or sweating - diarrhea - yawning (t) Clonidine |
Sources : Diagnostic Criteria from DSM-IV, Blueprints Psychiatry 3rd ed
Ovarian Tumors
1. Introduction
a. Malignant ovarian tumors are the leading cause of death from reproductive tract cancer.
b. Majority of ovarian tumors are benign.
c. General lifetime risk is 1.6% and 5% with a first degree family relative.
d. Lifetime risk with BRCA1 gene is 45% and with BRCA2 gene is 25%.
2. Clinical Findings
a. Symptoms and Signs
i. Most patients are asymptomatic.
ii. Mild nonspecific gastrointestinal symptoms or pelvic pressure
iii. Pelvic exam can detect early disease.
iv. Advanced disease can present with bloating, abdominal pain, ascites, and palpable abdominal mass.
b. Lab Findings
i. CA 125 level greater than 35 units can indicate malignancy.
ii. CA 125 elevated in 80% of epithelial ovarian cancer and only 50% in early disease.
c. Imaging Studies
i. Transvaginal Ultrasound for screening
ii. Ultrasound helps differentiate from benign and malignant neoplasm.
3. Differential Diagnosis for an Ovarian Mass
a. Functional
b. Benign Neoplastic
i. Premenopausal woman, asymptomatic, mobile, unilateral, simple cystic mass less than 7.5 cm
c. Potentially Malignant
d. Predictive factors include age, size of the mass, ultrasound configuration, CA 125 levels, symptoms, and symmetry
4. Treatment
a. Malignant neoplasm – surgical staging, abdominal hysterectomy, bilateral salpingo-oophorectomy
i. Advanced disease
1. removal of all visible tumor
2. post-operative chemotherapy
a. cisplatin or carboplatin with paclitaxel
b. Benign neoplasms – tumor removal or unilateral oophorectomy
5. Prognosis (5 yr survival)
a. Distant metastases – 17%
b. Local spread – 36%
c. Early disease – 89%
Source:
1. Tierney, Jr,
Normal Pregnancy | Preeclampsia | Severe Preeclampsia | |
Blood Pressure | Fall in first 24 weeks, rises to baseline by term | 140/90 after 20 weeks gestation | >160/100 |
Kidneys | GFR increases 50%, renal plasma flow increases serum urea and creatinine decrease; enhanced waste metabolite removal; glycosuria | Vasospasm and capillary endothelial swelling -> reduction in GFR Serum uric acid and creatinine increased Proteinuria > 300 mg in a 24 hour collection | proteinuria > 5 g/24h, oliguria (<500cc/24h) Oliguria <> |
Edema | Normal | Presenting sign but 1/3 don’t have it | |
Hemostatic | Venous stasis from hypercoagulable state | Systemic vasospasm, coagulation system activation, abnormal hemostasis Cycle – endothelial injury, platelet activation, platelet consumption | |
Prostanoid Changes | Both prostacyclin (PGI) and Thromboxane A2 (TXA) elevated, PGI > TXA | TXA > PGI PGI – vasodilator and inhibitor of platelet aggregation TXA – vasoconstriction and platelet aggregation | |
Autonomic | Increased sympathetic state – vasoconstriction | ||
Nitric Oxide | Reduced | ||
Free radical oxidation products | Increased | ||
Hematologic | Plasma vol inc, RBC mass inc à “physiologic anemia” of pregnancy Hgb 11.5 mg/dl WBC count increases Hypercoagulable state – inc fibrinogen, factor VII to X increase – venous stasis | - Thrombocytopenia - <100,000 class="MsoNormal">- fibrinogen decreased - coagulation time increased (PT, PTT) -Can progress to DIC | |
Hepatic | Signs of liver disease Spider angiomata and palmar erythema – elev estrogen Serum – dec albumin, elev alk phos, elev cholesterol Estrogen increased proteins – fibrinogen, thyroid hormone binding globulin, ceruloplasmin Hepatic enzymes – AST/ALT, PTT unchanged | 10% - transaminase elevation | impaired liver function (AST/ALT >70) |
Pulmonary | pulmonary edema | ||
Neurological | Cerebral or visual disturbances Headache | ||
GI | Epigastric pain - hepatic subcapsular hemorrhage -stretch or rupture of liver capsule | ||
Seizures | Severe cases -> Eclampsia |
HELLP Syndrome - hemolysis, elevated liver enzymes, low platelets - severe preeclampsia.
Sources:
1. Rubin, Emanuel . Rubin's Pathology: Clinicopathologic Foundations of Medicine. 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2005 : 986-7.
2. Tierney, Jr, Lawrence M., Stephen J. McPhee, and Maxine A. Papadakis. Current Medical Diagnosis & Treatment 2005. 44th ed. New York: McGraw Hill, 2005: 747-9.
| Chief Complaint | ||||||||||||
| chest pain and shortness of breath | ||||||||||||
| History of Present Illness | ||||||||||||
| 23 year old female with past medical history significant for birth control use of five years and 15 smoke pack years presents witch chest pain and shortness of breath. Four days prior to admission, she started to experience a dull, substernal pain with deep breaths. Two days prior to admission, she experienced shar pain in lower left anterior axillary line with deep breaths. One day prior to admission, she started to experience upper left sided chest pain. While at her Ob-Gyn office on the morning of admission, she was experiencing shortness of breath, and she was told to go to the ER. Currently, her chest pain is constant on the left side. She says she can walk ten steps before becoming short of breath. She denies palpitations, leg pain, nausea, vomiting, diarrhea, cough, pain radiation. Previously, she experienced chest pain during this current summer which went away in four days without hospital admission. | ||||||||||||
| Past Medical History | ||||||||||||
| Patient denies hypertension, diabetes, stroke, coronary artery disease, rheumatic fever, asthma, or spontaneous abortions. Patient has been on Depo-provera for five years prior to current birth control of Norgestrel. | ||||||||||||
| Past Surgical History | ||||||||||||
| Patien did not have previous surgeries. | ||||||||||||
| Medications | ||||||||||||
| Norgestrel Unisom | ||||||||||||
| Immunizations | ||||||||||||
| Patient has not received her pneumococcal, hepatitis, or flu vaccine. | ||||||||||||
| Allergies | ||||||||||||
| NKDA | ||||||||||||
| Family History | ||||||||||||
| Father is alive, 52 years old without hypertension, diabetes, coagulopathy, or coronary artery disease. Mother is alive, 46 years old. She has hypertension. She has no history of coronary artery disease, coagulopathy, or diabetes.Both grandmothers had strokes at old ages. Her family has no history of cancer or coagulopathy. | ||||||||||||
| Social History | ||||||||||||
| Alcohol - She drinks up to 12 beers during the weekend over one to two nights. Tobacco - She has been smoking 1.5 packs per day for 10 years Substance - She denies any substance abuse. Psychosocial - She denies any changes in her general behavior. She lives with her friend after leaving her family residence. Functional - She believes she has normal function. | ||||||||||||
| Review of Systems | ||||||||||||
| General: () weight loss () fever () night sweats () weakness/fatigue () appetiteEndocrine: () heat intolerance () decreased energy () thyroid/reanl dz () polydipsia () polyuriaLympatics: () lymphadenopathySkin: () itching () pale () palmar creases Hematology: () anemia () bruising () bleedingHead: () seizures () trauma () loss of conscioussness () headache () vertigo () dizzinessEyes: () visual changes (X) blurred vision () loss of vision () dischargeEars: () discharge () ear pain () tinnitus () ototoxic drug history () hearing lossNose: () discharge () rhinorrhea () epistaxisMouth and Throat: () lip cracking () gum soreness () gum hypertrophy () dryness () thirst () excessive salivation () throat pain () hoarsenessCardiorespiratory: (X) SOB () valvular disease (X) orthopnea (X) dyspnea on exertion () nocturia () edema (X) paroxysmal nocturnal dyspnea () cough () cyanosis () hemoptysisGastrointestinal () dysphagia () abdominal pain () vomiting () hematemesis () melena () hematochezia () change in appetite () diarrhea () constipation () jaundiceGenitourinary: () change in bladder function () change in amount () dysuria () hematuria () dischargeNeuropsychiatric: () weakness () motor/sensory deficit () depression () anxietyPain: Chest pain on left side | ||||||||||||
| Physical Exam | ||||||||||||
| General Appearance:Vital Signs:Temperature: 98.1 F Oxygen Saturation: 100% on RA Blood Pressure: 125/82 Respiratory Rate: 18 Pulse Rate: 117Skin/Nails:Head:Eyes:Ears:Nose:Throat/Mouth:Neck:Lymph:Pulmonary: CV:Abdomen:Breasts:Rectal:Genitals:Peripheral pulses:Musculoskeletal:Neurologic:Mental StatusCN ICN IICN III,IV, VI CN V, VIICN VIICN VIIICN IX, XCN XICN XIICerebellarDTRs | ||||||||||||
| Labs | ||||||||||||
| Troponin I <0.05,>D-Dimer 3.20 Imaging CT - Multiple pulmonary embolisms on the right upper lobe, right lower lobe, left upper lobe, and left lower lobe in the segmental and subsegmental branches. Her right middle lobe does not have a pulmonary embolism.
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| Assessment/Plan | ||||||||||||
23 year old female with a past medical history significant for smoking and contraceptive use presenting with multiple, acute pulmonary embolisms. She presented with some classic signs of pulmonary embolism including dyspnea and chest pain (1). 1. Tierney, Lawrence M., ed. Current Medical Diagnosis & Treatment. 44th ed. New York: McGraw Hill, 2005. | ||||||||||||
| Created with H and P |
Chest Pain |
| Non-Cardiac |
| Pulmonary |
|
| Gastrointestinal |
|
| Musculoskeletal |
Chostochondritis |
| Other |
psychiatric |
| Cardiac |
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Although CMDT appears as a tome of medicine at 1888 pages, its proven to be a good home reference book. Diseases are covered in a few pages, while still maintaining good attention to detail in presentation and management. This book is all text with a few tables and no pictures. More pages are dedicated to common diseases with varying presentations like pneumonia. It's main advantage over other books is it's updated every year. |
| Palm LifeDrive Its got a 4 gigabyte hard drive, which sets it apart from any other PDA on the market. Another distinguishing aspect is its price, $500. It might be more than I need for rotations at the hospital, but it would also serve as an mp3 player. | |
Treo 650 This PDA has everything bundled into one small package, including a a camera and a phone. I would only have to carry one device to the hospital, and its memory is expandable with SD cards. One drawback is its small size. The Treo has a much smaller screen than other PDAs after seeing it at an electronics store. The size is good for carrying it around as a phone, but I wouldn't be too happy staring at a small screen in the hospital. | |
Tungsten T5 The T5 is the top of the line flash drive based PDA, with a large 256 mb of internal memory. This is its main selling point, along with its fast processor and large screen. | |
Tungsten T3 The T3 is probably the best value for the money among the high end PDAs. Its got a large screen accessible by pulling open the PDA. Its a unique design, but I would rather have a large screen available at all times. | |
Tungsten E This is the minimum suggested PDA for rotations. Its got 32 mb of internal memory, which is enough for medical applications. |